Electrochemotherapy

About this approach

Electrochemotherapy applies brief electric pulses to a tumor after a chemotherapy drug is given, temporarily making cell membranes more permeable to the drug. It is mainly used in some countries for accessible skin or superficial tumors and differs from irreversible electroporation and pulsed electric field ablation.

Where it fits: Local treatment combining electric pulses with chemotherapy

Where this treatment is used

Clinical use is established in parts of Europe for selected cutaneous and subcutaneous tumors, but availability and regulatory status vary internationally. Evidence is strongest for local control and symptom relief in accessible lesions rather than treatment of widespread cancer throughout the body.

Procedure and practical considerations

Pain, swelling, skin changes, ulceration, bleeding, infection, muscle contractions, and anesthesia-related risks can occur. Large, deep, or nearby critical structures may not be suitable. The team should explain the drug, electrode approach, local-control goal, and plan for disease elsewhere.

Cancer guides that discuss this treatment

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Clinics reporting this approach

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