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Radiofrequency ablation for cancer

Cancer treatment & testing

Established local treatment for selected tumors

Radiofrequency ablation uses an image-guided probe and electrical energy to generate heat that destroys a planned area of tissue. It can treat selected tumors, including some in the liver, kidney or lung, and may also be used for pain from bone tumors. This is a local procedure rather than a whole-body cancer treatment. The team considers tumor size, location, nearby structures and other options before deciding whether a safe, complete treatment area can be created.

Information checked 2026-09-29 View sources ↓
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About this approach

Radiofrequency ablation uses an image-guided probe and electrical energy to generate heat that destroys a planned area of tissue. It can treat selected tumors, including some in the liver, kidney or lung, and may also be used for pain from bone tumors. This is a local procedure rather than a whole-body cancer treatment. The team considers tumor size, location, nearby structures and other options before deciding whether a safe, complete treatment area can be created.

Where it fits: Established local treatment for selected tumors

CURRENT CLINICAL USE

Where this treatment is used

RFA has an established role in selected local treatment pathways, especially when surgery is unsuitable or when a small tumor can be treated without a major operation. Its effectiveness depends on whether the tumor and an appropriate surrounding margin can be covered safely. Large tumors, proximity to sensitive structures and nearby blood flow may influence which ablation method is chosen. RFA differs from microwave ablation and cryoablation even though all aim to destroy a defined tissue volume. Treatment may be performed through the skin or during an operation. Follow-up imaging is needed to assess the treated area; residual or recurrent disease may require another procedure or a different cancer treatment.

WHAT TREATMENT MAY INVOLVE

Procedure and practical considerations

Possible complications include bleeding, infection, blood clots, pain and injury to nearby organs or tissue. Sedation or anesthesia adds its own risks. The organs treated determine additional concerns, such as liver-function changes or complications around the lung. Short-lived discomfort after ablation does not rule out a more serious problem.

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Sources

Source information checked: 2026-09-29. The links below identify the public and clinic-provided materials used for this page.

  1. Mayo Clinic: Radiofrequency ablation for cancer ↗Checked 2026-09-29
  2. Cambridge University Hospitals: Liver ablation patient guide ↗Checked 2026-09-29

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